HPLC Column, RP C4 Butyl, 5um, 4.0mm ID x 100mm Length, 100A. Cogent Brand. 1 EA. Special Order Item.
Additional Information:
Cogent RP C4™ is a reversed-phase HPLC stationary phase designed for the separation of hydrophobic and neutral compounds where less retention is desired than with traditional C8 or C18 phases. Manufactured using a four-carbon butyl ligand bonded to ultra-high purity silica and fully double end capped, this stationary phase provides reproducible chromatographic performance and is widely used as an alternative in USP methods requiring L26 chemistry. Its reduced hydrophobicity compared to longer-chain bonded phases makes it particularly useful for rapid analyses and method development studies.
683504-10P-4 is an HPLC column packed with 5 µm RP C4™ particles featuring a 100 Å pore size in a 4.0 mm ID x 100 mm format. The 100 mm length provides an excellent balance between chromatographic resolution and analysis speed, while the 5 µm particles allow operation at higher flow rates with lower backpressure than smaller particle columns. Typical operating flow rates are approximately 0.8–1.5 mL/min depending on mobile phase composition, temperature, and system configuration.
This column is commonly used for hydrophobic and neutral compounds in reversed-phase HPLC when reduced retention is desirable. The C4 bonded phase is often selected for scouting studies, method development, and routine analytical applications where shorter run times and faster equilibration are beneficial. Compared to C8 phases, RP C4™ typically provides lower retention, making it useful for compounds that may be excessively retained on more hydrophobic stationary phases.
Key Benefits
RP C4™ stationary phase
USP L26 equivalent chemistry
Butyl bonded phase
Fully double end capped
Ultra-high purity silica support
Less retention than C8 phases
Suitable for rapid analyses
Lower backpressure than smaller particle columns
5 µm particle size
Excellent for method scouting
Typical Applications
USP L26 methods
Method development
Method scouting
Hydrophobic compound analysis
Neutral compound analysis
Reversed-phase HPLC
Pharmaceutical analysis
Quality control testing
High-throughput analysis
Research and development
Specifications
Product Type: HPLC Column
Stationary Phase: RP C4™
USP Classification: L26
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double End Capped
Particle Size: 5 µm
Pore Size: 100 Å
Column Dimensions: 4.0 mm ID x 100 mm
Length: 100 mm
Typical Flow Rate: 0.8–1.5 mL/min
Brand: Cogent
Special Order Item Information
Please review the Special Order Item Information for complete details.
For pricing confirmation, availability, lead times, or application assistance, please contact MICROSOLV Customer Service.
Important Notes
Designed for hydrophobic and neutral compounds
Provides less retention than C8 stationary phases
Suitable for rapid reversed-phase separations
The 100 mm length provides a balance of resolution and analysis speed
5 µm particles allow higher flow rates with lower backpressure
Fully double end capped to minimize secondary interactions
Frequently used for method development and scouting studies
Excellent alternative for USP L26 methods
This is a Special Order Item